Lead in the Blood of Children

Lead is a major environmental health hazard for young children. Childhood exposure to lead contributes to learning problems, including reduced intelligence quotient (IQ) and reduced academic achievement, as well as behavioral problems.1 The Centers for Disease Control and Prevention (CDC) lowered the blood lead reference level from 5 micrograms lead per deciliter of blood (µg/dL) to 3.5 µg/dL in 2021 to identify children with elevated blood lead levels.2 A blood lead level above CDC's reference value is defined as "elevated" for purposes of identifying children for follow-up activities, such as environmental investigations and ongoing monitoring,3 but no level of childhood lead exposure can be considered safe,4 and adverse health effects can occur at much lower concentrations.1 Lead exposure has declined since the 1970s, due largely to the removal of lead from gasoline and paint. Children ages 1–5—the focus of this indicator—are particularly vulnerable because they frequently engage in hand-to-mouth behavior.

Indicator PHY4.A Percentage of children ages 1–5 with blood lead levels at or above 3.5 µg/dL, selected years 1988–1994 through 2017–March 2020
Indicator PHY4.A: Percentage of children ages 1–5 with blood lead levels at or above 3.5 µg/dL, selected years 1988–1994 through 2017–March 2020

NOTE: The reference level of 3.5 µg/dL was the 97.5th percentile of blood lead levels for children ages 1–5 in 2015–2016 and 2017–2018 cycles of the National Health and Nutrition Examination Survey (NHANES). The Centers for Disease Control and Prevention currently use this reference level to identify children with elevated blood lead levels. The NHANES program suspended field operations in March 2020 due to the COVID-19 pandemic. As a result, data collection for the 2019–2020 cycle was not completed. Therefore, data collected from 2019 to March 2020 were combined with data from the 2017–2018 cycle to create a 2017–March 2020 pre-pandemic file. This file covers 3.2 years of data collection. For more information, see https://wwwn.cdc.gov/nchs/nhanes/continuousnhanes/overviewbrief.aspx?Cycle=2017-2020.

SOURCE: National Center for Health Statistics, National Health and Nutrition Examination Survey.

Indicator PHY4.B Percentage of children ages 1–5 with blood lead levels at or above 3.5 µg/dL by race and Hispanic origin and poverty status, 2017–March 2020
Indicator PHY4.B: Percentage of children ages 1–5 with blood lead levels at or above 3.5 µg/dL by race and Hispanic origin and poverty status, 2017–March 2020

NOTE: NH = non-Hispanic origin. Persons of Mexican American origin may be of any race. Included in the total but not shown separately are persons who were American Indian or Alaska Native, Asian, Native Hawaiian or Other Pacific Islander, and of Two or more races. Data on race and Hispanic origin are collected separately but combined for reporting. Persons of Hispanic origin may be of any race. See the NOTE under PHY4.A for information about the reference level and data treatment.

SOURCE: National Center for Health Statistics, National Health and Nutrition Examination Survey.

  • In 2017–March 2020, the percentage of children ages 1–5 with elevated blood lead levels (at or above 3.5 µg/dL) was 1.4%. This percentage was 18.5% in 1999–2002 and 43.0% in 1988–1994.
  • In 2017–March 2020, 2.8% of Black, non-Hispanic children, 1.5% of Mexican American children, and 1.3% of White, non-Hispanic children had blood lead levels at or above 3.5 µg/dL. These differences were not statistically significant.
  • In 2017–March 2020, 1.7% of children living in poverty had blood lead levels at or above 3.5 µg/dL. This percentage was 29.6% in 1999–2004.

table icon PHY4.A HTML Table | PHY4.B HTML Table

1 National Toxicology Program. (2012). NTP monograph: Health effects of low-level lead. U.S. Department of Health and Human Services, National Institute of Environmental Health Sciences. http://ntp.niehs.nih.gov/go/36443

2 Ruckart P. Z., Jones R. L., Courtney J. G., Telfair, T. L., Jackson, W., Karwowski, M. P., Cheng, P-Y, Allwood, P., Svendsen, E. R., & Breysse, P. N. (2021, October 29). Update of the blood lead reference value — United States, 2021. Morbidity and Mortality Weekly Report, 70(43), 1509–1512. https://www.cdc.gov/mmwr/volumes/70/wr/mm7043a4.htm

3 Centers for Disease Control and Prevention. (2012, May 5). CDC response to Advisory Committee on Childhood Lead Poisoning Prevention recommendations in "Low level lead exposure harms children: A renewed call for primary prevention." Morbidity and Mortality Weekly Report, 61(20), 383. https://www.cdc.gov/lead-prevention/about/index.html

4 Advisory Committee on Childhood Lead Poisoning Prevention. (2012). Low level lead exposure harms children: A renewed call for primary prevention. Centers for Disease Control and Prevention. https://stacks.cdc.gov/view/cdc/11859